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Decreased Phenytoin Levels in Patients Receiving Chemotherapy Am J Med 87:505-510, Grossman,S.A., 1989 See this aricle in Pubmed Article Abstract These observations are important to physicians treating patients who are receiving phenytoin.Serious consequences can be avoided by expecting changes in phenytoin dosage requirements after the administration of chemotherapy,monitoring serum levels frequently,and making appropriate adjustments in phenytoin dosages.Prospective evaluations are needed to confirm these observations,to define the chemotherapeutic agents that predispose patients to these alterations in phenytoin's pharmacology,and to determine if drugs other than phenytoin are affected by the administration of chemotherapy.

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(click to filter results - removes previous filter) anticonvulsants,blood level determination of carmustine chemotherapy,CNS treatment and complications with cis-platinum dilantin dilantin,serum level

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